Hadine Joffe Selected Research

Hot Flashes

5/2022	A hormonal therapy for menopausal women with MS: A phase Ib/IIa randomized controlled trial.
6/2021	Sleep and endocrine therapy in breast cancer.
1/2020	Lights on MsFLASH: a review of contributions.
10/2016	Independent Contributions of Nocturnal Hot Flashes and Sleep Disturbance to Depression in Estrogen-Deprived Women.
2/2016	Armodafinil for fatigue associated with menopause: an open-label trial.
6/2015	Effects of estrogen and venlafaxine on menopause-related quality of life in healthy postmenopausal women with hot flashes: a placebo-controlled randomized trial.
4/2015	Duration of menopausal vasomotor symptoms over the menopause transition.
1/2015	Effects of estradiol and venlafaxine on insomnia symptoms and sleep quality in women with hot flashes.
7/2014	Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine for vasomotor symptoms: a randomized clinical trial.
4/2014	Increased hot flash severity and related interference in perimenopausal human immunodeficiency virus-infected women.

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Hadine Joffe Research Topics

Disease

25	Hot Flashes 05/2022 - 07/2006
12	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2022 - 12/2006
6	Bipolar Disorder (Manic Depressive Psychosis) 04/2011 - 03/2003
5	Breast Neoplasms (Breast Cancer) 11/2021 - 09/2010
5	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2008 - 03/2003
4	Major Depressive Disorder (Major Depressive Disorders) 07/2022 - 03/2011
4	Depressive Disorder (Melancholia) 12/2021 - 09/2006
4	Pain (Aches) 06/2015 - 06/2007
3	Sleep Deprivation 01/2022 - 06/2014
2	Premenstrual Dysphoric Disorder 01/2022 - 12/2007
2	Hyperprolactinemia 01/2014 - 01/2008
2	Amenorrhea 08/2012 - 01/2008
2	Epilepsy (Aura) 01/2008 - 06/2006
2	Hyperandrogenism 12/2006 - 06/2006
1	Cognitive Dysfunction 07/2022
1	Alzheimer Disease (Alzheimer's Disease) 07/2022
1	Dementia (Dementias) 07/2022
1	Mood Disorders (Mood Disorder) 01/2022
1	Sleep Wake Disorders 06/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2021
1	Disorders of Excessive Somnolence (Hypersomnia) 01/2020
1	Substance-Related Disorders (Drug Abuse) 01/2018
1	Sleep Apnea Syndromes (Sleep Apnea) 01/2017
1	Apnea 01/2017
1	Obstructive Sleep Apnea 01/2017
1	Syndrome (Syndromes) 02/2016
1	Fatigue 02/2016
1	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2014
1	Neoplasms (Cancer) 12/2013
1	Insulin Resistance 10/2012
1	Migraine Disorders (Migraine) 01/2008
1	Psychotic Disorders (Schizoaffective Disorder) 01/2008
1	Hemorrhage 12/2007
1	Chronic Disease (Chronic Diseases) 01/2007
1	Body Weight (Weight, Body) 12/2006
1	Hirsutism 06/2006

Drug/Important Bio-Agent (IBA)

11	Estrogens (Estrogen)FDA Link 01/2022 - 09/2006
10	Hormones (Hormone)IBA 07/2022 - 07/2006
9	Estradiol (Delestrogen)FDA LinkGeneric 01/2022 - 07/2011
6	Escitalopram FDA Link 01/2020 - 01/2011
6	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 01/2020 - 09/2010
4	Antidepressive Agents (Antidepressants)IBA 01/2018 - 07/2006
4	Gonadotropin-Releasing Hormone (GnRH)FDA Link 10/2016 - 09/2013
4	Valproic Acid (Depakote)FDA LinkGeneric 01/2008 - 03/2003
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 04/2011
3	Eszopiclone (Lunesta)FDA Link 01/2012 - 12/2006
2	AndrogensIBA 12/2021 - 06/2006
2	Pharmaceutical PreparationsIBA 06/2021 - 01/2014
2	beta-Aminoethyl Isothiourea (AET)IBA 01/2021 - 09/2012
2	Tamoxifen FDA LinkGeneric 01/2021 - 09/2012
2	Aromatase InhibitorsIBA 01/2021 - 09/2012
2	Contraceptive Agents (Contraceptives)IBA 01/2020 - 01/2007
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2018 - 03/2011
2	Progesterone FDA LinkGeneric 06/2014 - 01/2011
2	ProlactinIBA 01/2014 - 01/2007
2	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2014 - 01/2007
2	Antipsychotic Agents (Antipsychotics)IBA 01/2014 - 01/2008
2	Leuprolide (Lupron)FDA LinkGeneric 09/2013 - 09/2012
2	Duloxetine Hydrochloride (Cymbalta)FDA Link 06/2013 - 06/2007
2	Hypnotics and Sedatives (Sedatives)IBA 07/2011 - 09/2010
2	Zolpidem (Ambien)FDA LinkGeneric 07/2011 - 09/2010
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2011 - 09/2010
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2008 - 06/2006
2	Oral ContraceptivesIBA 12/2007 - 12/2003
1	mahuang-tangIBA 07/2022
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2022
1	OrexinsIBA 01/2022
1	NeuropeptidesIBA 01/2022
1	Orexin Receptor AntagonistsIBA 01/2022
1	suvorexantIBA 01/2022
1	Orexin ReceptorsIBA 01/2022
1	CarbohydratesIBA 01/2022
1	Therapeutic UsesIBA 02/2016
1	Modafinil (Provigil)FDA Link 02/2016
1	N-formylmethionylphenylalanine (FMP)IBA 04/2015
1	Aripiprazole (Abilify)FDA Link 01/2014
1	Glucose (Dextrose)FDA LinkGeneric 10/2012
1	Insulin (Novolin)FDA Link 10/2012
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 09/2012
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 09/2012
1	Dihydrotachysterol (AT 10)IBA 08/2012
1	Serotonin (5 Hydroxytryptamine)IBA 09/2010
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 09/2010
1	Serotonin and Noradrenaline Reuptake InhibitorsIBA 09/2010
1	Paroxetine (Paxil)FDA LinkGeneric 02/2008
1	PregnanediolIBA 12/2007
1	Follicle Stimulating Hormone (Follitropin)FDA Link 12/2007
1	GlucuronidesIBA 12/2007
1	Luteinizing Hormone (Lutropin)FDA LinkGeneric 12/2007
1	Progestins (Progestagens)IBA 09/2006
1	Ethinyl Estradiol (Estinyl)FDA LinkGeneric 09/2006
1	Norethindrone Acetate (Norlutate)FDA LinkGeneric 09/2006
1	LithiumIBA 06/2006

Therapy/Procedure

17	Therapeutics 07/2022 - 07/2006
2	Drug Therapy (Chemotherapy) 06/2021 - 12/2013
2	Aftercare (After-Treatment) 03/2013 - 01/2011
1	Meditation 11/2021
1	Salpingo-oophorectomy 01/2021
1	Ovariectomy (Oophorectomy) 08/2012
1	Hysterectomy 08/2012